New Venus White Pro Studies

New studies demonstrate that Heraeus Kulzer’s Venus White Pro whitening system is proven to whiten teeth up to 8.4 shades with virtually no sensitivity!


Effectiveness and color rebound effect of a 22% carbamide peroxide

By JC Ontiveros, MS Eldiwany, W Wang, M Eldiwany and RD Paravina, University of Texas, Houston, Texas


Objective

To evaluate the effectiveness and colour rebound effect of a 22% carbamide peroxide (CP) at-home whitening system.

Methods

A total of 21 subjects were recruited for an at-home tooth whitening clinical study. Subjects were treated overnight for 2 weeks with 22% CP (Venus White Pro, Heraeus Kulzer). Visual color measurement was performed by three color normal evaluators using the Vita Classical (VC) and the 3D Bleachedguide (BG). Instrumental color measurements were performed using an intraoral spectrophotometer (Vita Easyshade Compact). Color measurements were taken on a canine and central incisor at baseline, 2, 3, and 4 weeks. Wilcoxon matched-pair signed-rank test for group comparisons and Bonferroni correction was used to adjust for multiple testing at the 0.05 level of significance.

Results

Means (sd) for visual and instrumental whitening-dependent colour changes are listed in the table; SGU=shade guide units, DE= total colour change.


 2 weeks minus baseline3 weeks minus baseline4 weeks minus baseline
 IncisorCanineIncisorCanineIncisorCanine
SGU(BG)3.9(1.7)5.8(2.1)3.7(1.7)5.6(2.3)3.7(1.3)5.4(2.2)
SGU(VC)5.2(2.8)8.4(3.5)4.9(2.4)8.0(3.5)4.8(2.5)8.0(3.5)
DE*(ES)7.0(2.9)10.2(4.7)7.1(2.5)9.1(4.8)6.7(2.7)9.9(4.2)

For visual shade evaluation with VC and BG, there was a statistically significant decrease in SGU from baseline and each subsequent week among all measurements, p<0.001. For instrumental measurements, there was no difference from week 2 to week 3 for canines and generally no difference between week 3 and week 4 in all parameters for incisors.

Conclusions

Visual and instrumental measurements evaluation showed clinical whitening-dependent rebound occurred 1 week post bleaching. In general, color stabilised at 2 weeks post bleaching.



Clinical evaluation of sensitivity using 22% carbamide peroxide gel

By MS Eldiwany, JC Ontiveros, RD Paravina, M Eldiwany and W Wang, University of Texas, Houston, Texas


Objective

To clinically evaluate the sensitivity of commercially available 22% carbamide peroxide with 3% potassium nitrate, at home bleaching system.

Methods

A total of 21 subjects with no history of previous tooth whitening and no tooth sensitivity were recruited for at-home whitening clinical study using Venus White Pro 22% carbamide peroxide (Heraeus Kulzer). Subjects were treated nightly for 2 weeks with a maxillary custom tray. Sensitivity rating from 0-10 with zero representing no pain and 10 representing worst possible pain was documented at the initial appointment. Subjects were asked to document their sensitivity every morning for 14 days during treatment, and 14 days post bleaching. Wilcoxon matched-paired signedrank test and Bonferroni correction for multiple comparisons were used at the 0.05 level of significance.

Results

Mean, standard deviation, and median sensitivity scores are as follows:


Average sensitivityWeek 1Week 2Week 3Week 4
Mean (SD)1.2(1.2)1.7(2.0)0.2(0.4)0.1(0.3)
Median0.780.7800
25%, 75% quantile0.07,2.140.07,2.570,0.070,0

There was no statistically significant difference between week 1 and 2 (p=0.17) or week 3 and 4 (p=0.19). There was a statistically significant difference, between week 1 and 3, week 1 and 4, week 2 and 3, week 2 and 4; p<0.01, respectively.

Conclusions

Patients receiving nightly treatment with a commercially available 22% carbamide peroxide 3% potassium nitrate, at-home bleaching agent reported low sensitivity levels with a mean value of below 2 on a 0-10 scale.